Benzathine Benzylpenicillin for Injection- Newlystar (Ningbo) Medtech Co., Ltd.

Newlystar (Ningbo) Medtech Co., Ltd.

We only export finished medicines. We are a professional trading company, if you must make deal with manufacturer, please find manufacturer directly.
We export to Europe, to Latin American, to Asia, to Africa. We have clients in more than 30 countries.
Each year, we have big deal with a lot manufacturers in China, because the quantity is big, our price is competitive.
And to make our business longer and stable, we only deal with manufacturers with good quality.

We have a quality department dealing with registration dossier and help manufacturers pass higher GMP inspection. We are the best one in China in this issue.

Above are features of Newlystar.
If you want read more information about our company, please go ahead. But usually, offical company introduction, doesn't have many useful information.(That is my personal opinion.)

Newlystar Medtech cooperate with state of the art facilities in China and export medicines to 30+ countries worldwide. Include East Europe, Central and southeast Asia, Latin America, Africa etc. We also contract manufacture for European companies.

Newlystar-Medtech is a well established and professional supplier of Finished Pharmaceutical, Active Pharmaceutical Ingredient(API) and Medical Devices. With a proven track record of passed years, Newlystar-Medtech has been recognized by her customers as a high-quality and reliable supplier not only on products, but also on assistance for audit and improvement of GMP level, quality management system, EHS management system and registration dossier support, etc.
The essence of Newlystar-Medtech's activites, is a commitment to her customers with professional service and high-quality products with effective cost and innovative solutions. All pharmacists work in Newlystar-Medtech like a bridge link the customers and Chinese manufacturers, especially, their professional working is to make the formulation manufacturers who is familiar with Chinese Pharmacopoeia to understand well the international requirement, to ensure the success of customers.
The advantages on professional working and strongly representative base on first-class manufacturing partners in China, enable Newlystar-Medtech to provide her customers with a wide range and high-tech products, best services and capabilities for their actions in tender, distributing and improvement in their national healthcare system. Newlystar-Medtech also dedicates herself to sourcing quality medical products for Chinese market.

Services and capabilities include:
1. Sourcing quality manufacturer
2. Contract manufacturing;
3. Conduct audits to suppliers (pharmaceutical plants);
4. Consultation on audit and improvement of GMP level, quality management system and EHS management system;
5. Regulatory support, registration dossier working;

Newlystar Medtech, your professional one-stop China Souring Partner.

Home>Product>Benzathine Benzylpenicillin for Injection

Benzathine Benzylpenicillin for Injection

FOB Price:Get Latest Price >
Min.Order:50000 Vial(s)
Payment Terms:L/C , T/T

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Newlystar (Ningbo) Medtech Co., Ltd.

Business Type:Trader

Country/Region:China

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8/10

Product Information

Dosage Form:Powder
Route of Administration:Intravenous Drip
Shelf Life:3 years
Storage:Sealed

Description

Product : Benzathine Benzylpenicillin for Injection

Specification : 0.6mega; 1.2mega; 2.4mega

Standard : BP, USP

Description :

Benzylpenicillin is a natural substance derived from Penicillium notatum. It consists of a thiazolidone ring connected to a beta-lactam ring. It is bactericidal against streptococci, neisseriae, many anaerobes and spirochaetes.

After intramuscular injection, peak plasma concentrations are usually reached within 12-24 hours and are usually detectable for 1- 4 weeks. It is widely distributed throughout the body and is excreted mainly in the urine.

Uses: Streptococcal pharyngitis. Primary and secondary prophylaxis of rheumatic fever.

Dosage and administration:

Primary prophylaxis:

Children < 30 kg 600,000 IU, a single injection

Children 30 kg and adults

1,200,000 IU, a single injection

Secondary prophylaxis:

Children < 30 kg 600,000 IU, every 3-4 weeks

Children 30 kg and adults

1,200,000 IU, every 3-4 weeks

The vial is diluted in sterile water to allow for a homogeneous suspension to be obtained to avoid obstruction of the injecting needle. A needle gauge of #19 or #20 is preferred. Smaller bore needles have been noted to be more easily obstructed. The injection should be deep into the gluteus maximus muscle. More superficial injections allow the benzathine benzylpenicillin to remain in the subcutaneous tissue leading to decreased absorption and lower serum levels. Care should be taken that the whole content of the vial is fully removed and injected.

Contraindications: Known hypersensitivity to penicillin or cefalosporins.

Precautions: Facilities should be available for treating anaphylaxis whenever penicillin is used. A careful history should be taken with regard to previous allergic reactions.

If skin rashes develop, the patient another antimicrobial should be given.

Important caution: Many hypersensitivity reactions are reported with penicillin ranging from skin rashes to immediate anaphylaxis which may be fatal. The overall incidence of hypersensitivity reactions is from 2 to 5 %. Anaphylaxis is very rare and occurs in about 1/10 000 injections. Death has been reported in about 1/30 - 50 000 injections. It should be emphasized that many anaphylactic reactions occur in severely ill rheumatic heart disease patients who are at risk of life-threatening arrhythmias. They may have an arrhythmia associated with shock mimicking anaphylaxis.

Use in pregnancy: There is no evidence of teratogenicity with benzathine benzylpenicillin. It can be used during pregnancy.

Adverse reactions: The most common adverse effect of these substances are hypersensitivity reactions that range in severity from skin rashes to immediate anaphylaxis.

Pain and sterile inflammation can occur at the site of intramuscular injection.

Accidental injection into a peripheral nerve causes pain and dysfunction.

Nephropathy manifested as interstitial nephritis has been reported.

Neutropenia and thrombocytopenia have occurred rarely.