Amlodipine Besylate Tablets

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Newlystar (Ningbo) Medtech Co., Ltd.

Business Type:Trader

Country/Region:China

Ddu Verified

HOT Rank

6/10

Product Information

  • Dosage Form:Injection
  • Route of Administration:Oral
  • Shelf Life:3 years
  • Storage:Sealed

Description

Product : Amlodipine Besylate Tablets

Specification : 2.5mg, 5mg, 10mg

Standard : USP

Packing : 10’s/blister


Description :

Amlodipine is a long-acting 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, amlodipine prevents calcium-dependent myocyte contraction and vasoconstriction. A second proposed mechanism for the drug’s vasodilatory effects involves pH-dependent inhibition of calcium influx via inhibition of smooth muscle carbonic anhydrase. Some studies have shown that amlodipine also exerts inhibitory effects on voltage-gated N-type calcium channels. N-type calcium channels located in the central nervous system may be involved in nociceptive signaling and pain sensation. Amlodipine is used to treat hypertension and chronic stable angina.


Indication

For the treatment of hypertension and chronic stable angina. 


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