Hydrocortisone Cream

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Newlystar (Ningbo) Medtech Co., Ltd.

Business Type:Trader

Country/Region:China

Ddu Verified

HOT Rank

8/10

Product Information

  • Dosage Form:Cream
  • Route of Administration:Local Application
  • Shelf Life:3 years
  • Storage:Sealed

Description

Product : Hydrocortisone Cream

Specification : 1%, 15g

Standard : BP, USP

Packing : one tube/box


Description :

The topical corticosteroids constitute a class of primarily synthetic steroids used as anit-inflammitory and antipruritic agents. Hydrocortisone is a member of this class. 


Pharmacokinetics

The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings.

Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin increase percutaneous absorption. Occlusive dressings substantially increase the percutaneous absorption of topical corticosteroids. Thus, occlusive dressings may be a valuable therapeutic adjunct for treatment of resistant dermatoses. 

Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Corticosteroids are bound to plasma proteins in varying degrees. Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys. Some of the topical corticosteroids and their metabolites are also excreted by the bile.

 

Indications and Usage :


Hydrocortisone cream is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.


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